Dotinurad Impurity 194 CAS 50910-60-6 (free base)
| CAS No. | 50910-60-6 (free base) |
| Molecular Formula | C8H11NO3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Dotinurad Impurity 194 (CAS 50910-60-6 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C8H11NO3SHCl and a molecular weight of 237.70 g/mol.
Structurally, Dotinurad Impurity 194 (C8H11NO3SHCl) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 237.70 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H11NO3S HCl |
| Molecular Weight | 237.70 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 118 (CAS 127817-86-1)
- Dotinurad (CAS 1285572-51-1)
- Dotinurad Impurity 11 (CAS 1285572-54-4)
- Dotinurad Impurity 3 (CAS 1285572-55-5)
- Dotinurad Impurity 7 (CAS 1285572-63-5)
- Dotinurad Impurity 109 (CAS 1285572-82-8)
- Dotinurad Impurity 136 (CAS 1285572-83-9)
- Dotinurad Impurity 5 (CAS 1285572-89-5)
Recommended Standards
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